Brain Inflammation A Hallmark Of Autism, Large-Scale Analysis Shows

[Schafer Autism Report]

	Read this report online     Large text, printer version
December, 2014 p.                                                  Reader Supported.

Follow SAR Editor Lenny Schafer Daily Updates Here RESEARCH Brain Inflammation A Hallmark Of Autism, Large-Scale Analysis Shows Johns Hopkins study is largest so far of gene expression in autism brains        hopkinsmedicine.org The human brain using colors and shapes to show neurological differences between two people. Credit: Arthur Toga, University of California, Los Angeles via NIGMS.       While many different combinations of genetic traits can cause autism, brains affected by autism share a pattern of ramped-up immune responses, an analysis of data from autopsied human brains reveals. The study, a collaborative effort between Johns Hopkins and the University of Alabama at Birmingham, included data from 72 autism and control brains. It was published online today in the journal Nature Communications.       “There are many different ways of getting autism, but we found that they all have the same downstream effect,” says Dan Arking, Ph.D., an associate professor in the McKusick-Nathans Institute for Genetic Medicine at the Johns Hopkins University School of Medicine. “What we don’t know is whether this immune response is making things better in the short term and worse in the long term."       The causes of autism, also known as autistic spectrum disorder, remain largely unknown and are a frequent research topic for geneticists and font-size: 11px;neuroscientists. But Arking had noticed that for autism, studies of whether and how much genes were being used — known as gene expression — had thus far involved too little data to draw many useful conclusions. That’s because unlike a genetic test, which can be done using nearly any cells in the body, gene expression testing has to be performed on the specific tissue of interest — in this For rest of today's SAR click here: www.sarnet.org/frm/forsar.htm   Today's SAR newslist is human compiled and provided through the support of paid subscriptions.                   - THANK YOU - $35for 1 year - or free! www.sarnet.org

In This Issue: RESEARCH • Brain Inflammation A Hallmark Of Autism, Large-Scale Analysis Shows • Molecular Network Identified Underlying Autism Spectrum Disorders • Preeclampsia During Mother's Pregnancy Associated With Greater Autism Risk • Autism and Air Pollution: New Study Bolsters Suspected Link • Minute Movements of Autistic Children And Their Parents Provide Clue To Severity of Disorder • Diverse Autism Mutations Lead To Different Disease Outcomes • Project Pinpoints 12 New Genetic Causes of Developmental Disorders • Missing Gene Linked To Autism • 'Deep Learning' Finds Autism, Cancer Mutations In Unexplored Regions Of Genome • Largest Source of Autism Research Data To Date Created • Fine Particulate Air Pollution Linked With Increased Autism Risk • Boys With Regressive Autism, But Not Early Onset Autism, Have Larger Brains • Motor Coordination Issues In Autism Are Caused By Abnormal Neural Connections • Brain Anatomy Differences Between Autistic, Typically Developing Individuals Are Indistinguishable • Highlighted Study of the Month – MIND Institute CARE • Children with Autism Who Live With Pets Are More Assertive • Autistic Children Can Pose Barrier To Housing TREATMENT • How Music Class Can Spark Language Development • Are You Helping Your Toddler's Aggressive Behavior? • Efficacy and Safety of New Anti-Epileptic Drug Revealed By Phase III Study • Fragile X Study Offers Hope of New Autism Treatment • Parent Intervention Best For Helping Toddlers With Autism 'Schafer Autism Report' Now an App on iPhone, iPad and Droid!     DO SOMETHING ABOUT AUTISM NOW . . . Read, then Forward the Schafer Autism Report. $35 for 1 year - or free! www.sarnet.org Now's the perfect time to order your free Puzzle Piece kits and launch an autism awareness campaign in your community. When we raise the funding necessary, ARI will see that important research is done, including the large-scale, independent study of vaccinated vs. unvaccinated children Click here. Follow SAR Editor LennySchafer DailyUpdates The Autism Community Supports the Schafer Autism Report . . . Read, then Forward the Schafer Autism Report. $35 for 1 year - or free! www.sarnet.org Follow SAR Editor Lenny Schafer Daily Updates Here

Copyright Notice: The above items are copyright protected. They are for our readers' personal education or research purposes only and provided at their request. Articles may not be further reprinted or used commercially without consent from the copyright holders. To find the copyright holders, follow the referenced website link provided at the beginning of each item.

Lenny Schafer edi...@sarnet.org                                              The Schafer Autism Report is a non-profit corporation

Vol. 18 No. 5                                                                     Unsubscribe here: www.sarnet.org/frm/unsub2.htm