This mailing list is mostly for sharing information about using the MultiValue features of Caché. You might get more/better responses on the general Caché
Community. There is a list of Intersystems's communities at
http://www.intersystems.com/community.
Have you talked to your application vendor or the 3rd party provider of the updated cache.dat? Start there if you haven't.
In general, you can connect a cache.dat to a different cache instance. What kind if errors are you getting?