These logs of "The response for X has the self link Y" are developer warnings that are harmless and often can be ignored. They do occur for most sites, especially on item pages and there is an open ticket to eventually clean these up:
https://github.com/DSpace/DSpace/issues/8577
Occasionally though, lots of these can be a sign of something else going on - are you seeing any additional error messages or buggy behavior on the UI pages where the warnings were triggered? If not, these logs can be safely ignored.
Best,
-Lia