Inhibition of matrix metalloproteinase-9 rescues neurons ...
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Oct 26, 2005, 1:08:26 PM10/26/05
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to Apoptosis Research
A new study published in the Journal of Neuroscience indicated that laminin degradation by MMP-9 induced neuronal apoptosis in a mouse model of transient focal cerebral ischemia. Further, the highly specific inhibitor SB-3CT blocked MMP-9-mediated laminin degradation and rescued neurons from apoptosis.