Raloxifene Vs Tamoxifen Gyno - Beneficial effects of raloxifene and tamoxifen in the treatment of .
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r/gynecomastia • 1 yr. ago UniquelyDefined Positive Experiences on Tamoxifen or Raloxifene This subreddit seems to be exclusively a surgery cheerleading circle, so I want to start by saying that I've so far seen noticeable and good results on Tamoxifen. That's why I want to hear other people's positive stories about Tamoxifen or Raloxifene.
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Breast cancer chemoprevention: Drugs that reduce risk
Gynecomastia refers to an enlargement of the male breast caused by benign proliferation of the glands ducts and stromal components including fat. It is the most common form of breast swelling seen in adolescent males. During pubertal development, gynecomastia can develop as a result of transient relative imbalances between androgens and estrogens.
Gynecomastia: A systematic review of pharmacological treatments
Raloxifene is used mostly to prevent and treat osteoporosis (very weak bones) in post-menopausal women. When used to lower the risk of breast cancer, these drugs are typically taken for 5 years. Both drugs are pills taken once a day. Tamoxifen also comes in a liquid form.
Hormone Therapy for Breast Cancer Fact Sheet - NCI
Some improvement was seen in 86% of patients receiving tamoxifen and in 91% receiving raloxifene, but a greater proportion had a significant decrease (>50%) with raloxifene (86%) than tamoxifen (41%). No side effects were seen in any patients.
Breast Cancer Prevention: Tamoxifen and Raloxifene
As a result of these trials, both tamoxifen and raloxifene have been approved by the FDA to reduce the risk of developing breast cancer in women at high risk of the disease. Tamoxifen is approved for this use regardless of menopausal status. Raloxifene is approved for use only in postmenopausal women.
The Use of Tamoxifen and Raloxifene for the Prevention of Breast Cancer .
A randomized controlled trial reported in abstract form showed a lack of effect of the aromatase inhibitor anastrazole. 30 The ideal agent for treatment of gynecomastia would selectively block estrogen effect in breast tissue, as is the case with tamoxifen and raloxifene. Tamoxifen, an anti-estrogen, has traditionally been used in the treatment .
The Study of Tamoxifen and Raloxifene (STAR): Questions and Answers
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EastEnder2019 Gyno obliterated by Raloxifene - success Hey all, It's been a while since I posted and I thought I'd provide some useful insights into what worked *for me* to eliminate my gynecomastia. My gyno came on slowly and was brought on by a combination of factors that messed with my TRT.
Tamoxifen vs. Raloxifene - Medicalopedia
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Beneficial effects of raloxifene and tamoxifen in the . - PubMed
Tamoxifen and raloxifene increase risk for venous thromboembolic events; tamoxifen increases risk more than raloxifene ( Table 2 3, 4 ), and the potential for harms is greater in older.
Raloxifene for Gyno: Best Protocol to Reverse Gynecomastia - Sarms. io
Results Mean (SD) age of treated subjects was 14. 6 (1. 5) years with gynecomastia duration of 28. 3 (16. 4) months. Mean reduction in breast nodule diameter was 2. 1 cm (95% CI 1. 7, 2. 7, P <. 0001) after treatment with tamoxifen and 2. 5 cm (95% CI 1. 7, 3. 3, P <. 0001) with raloxifene.
Gyno obliterated by Raloxifene - success : r/Testosterone - Reddit
Raloxifene is used to reduce the risk of invasive breast cancer if you're at high risk and you've undergone menopause (postmenopausal). You're considered at high risk if you score greater than 1. 7% on the Gail model. Raloxifene is also used for prevention and treatment of the bone-thinning disease osteoporosis in those who've undergone menopause.
Beneficial effects of raloxifene and tamoxifen in the treatment of .
Key Takeaways Raloxifene is the most effective drug for reversing gynecomastia (gyno) without surgery. Raloxifene has been observed to reverse pre-existing gyno lumps, even when other drugs like Letrozole and Nolvadex have failed.
Raloxifene for gyno?! | MESO-Rx Forum
Marring this otherwise perfect story is the disquieting observation that in the STAR trial the incidence of noninvasive breast cancer was 40% lower for women randomized to tamoxifen than those randomized to raloxifene, and ductal carcinoma in situ comprised 54% of these in situ cancers (). The clinical relevance is obvious in that >20% of newly diagnosed breast cancers projected for 2007 will .
Medication Use to Reduce Risk of Breast Cancer: Recommendation . - AAFP
arashas1 • 1 yr. ago Nolva always does a better job of reversing my gyno flair One 60 mg dose followed by another 6 days of 40 mg completely removes a pea sized gyno. However sides are really bad for me. Libido will be non-existent. Very bad joint pains, vision issues and absolutely no desire to work or go to gym.
Raloxifene vs. Tamoxifen: 6 Similarities and Differences - GoodRx
The Study of Tamoxifen and Raloxifene. The NSABP's Study of Tamoxifen and Raloxifene (STAR) was a double-blinded, randomized clinical trial (Fig. 1) that began with 19,747 postmenopausal women who were at least 35 years of age and had a history of lobular carcinoma in situ (LCIS) treated by local excision alone or a modified Gail score demonstrating a 5-year risk for invasive breast cancer .
My experience with Tamoxifen vs Raloxifene for pubertal gyno
The Study of Tamoxifen and Raloxifene (STAR) is a clinical trial (a research study conducted with people) comparing the drug raloxifene (Evista®) with the drug tamoxifen (Nolvadex®) in reducing the incidence of breast cancer in postmenopausal women who are at an increased risk of developing the disease.
How To Get Rid Of Gyno Without Surgery - Raloxifene For Gyno
Also this info may not just benefit guys that take SSRIs, if you google "raloxifene vs tamoxifen for gyno" everything points to ralox hands down. Hopefully good things to come. . 2 Oct 30, 2013 #10 Dr JIM Well-known Member. That's one huge leap to suggest Relafen is superior to Tamoxifen based on a few PREPUBERTAL STUDIES! .
Management of adolescent gynecomastia: an update - PMC
Adolescence is one of the three phases in life with the highest incidence of gynecomastia (pubertal or adolescence gynecomastia), with the other two peaks being infancy and old age ( 2 ). The reported prevalence of pubertal gynecomastia (PG) is up to 70% ( 2 ).
Tamoxifen or Raloxifene in Postmenopausal Women for Prevention of .
Raloxifene: 60mg daily for 10 days ONLY. Then 30mg daily until gynecomastia is reversed. Recommended Supplementation During Raloxifene Treatment: Vitamin D and Calcium are recommended during Raloxifene treatment. 5000 IU vitamin D daily, and 500 mg of Calcium daily. This protocol above will take time. This is not a 2 week process.
Positive Experiences on Tamoxifen or Raloxifene : r/gynecomastia - Reddit
Both tamoxifen and raloxifene can lower the risk of invasive breast cancer (tamoxifen by about 50% and raloxifene by about 38%) in women at high risk* [1]. Both drugs also lower the risk of non-invasive breast cancer, such as ductal carcinoma in situ (DCIS), in women at high risk [1]. Tamoxifen
Tamoxifen and Raloxifene for Breast Cancer Risk . - Susan G. Komen
Yes but it takes time and you have to be patient and consistent with the dosages daily. ConcentratedMurder • 2 yr. ago. Tamoxifen is garbage compared to ralox. Ralox hits harder with less sides and is more effective at shrinking aged gyno. Accomplished_Pop_440 • 2 yr. ago.
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However, Tamoxifen is Anti-Estrogenic in premenopausal women (can itself cause osteoporosis) that's why Raloxifen is more famous for this indication. Tamoxifen is agonist on endometrial tissue (risk of cancer) while Raloxifen is antagonist on endometrial tissue (no risk of cancer). Both are agonist on liver tissue, therefore they may cause .