According to "Vitamin B6 Therapy: Nature's Versatile Healer," P5P may help relieve symptoms of seborrheic dermatitis, premenstrual syndrome, autism and certain types of anemia. The recommended dose of P5P varies based on the specific deficiency or medical condition you want to treat from 2. 5 mg to 50 mg daily.
Vitamin B6 has several derivatives, including pyridoxal, pyridoxal 5-phosphate (p5p) and pyridoxamine. These are all important compounds involved in numerous biological functions. In fact, vitamin B6 is used by the body every single day and plays a major role in everything from movement to memory, energy expenditure and blood flow.
Snapshot Proponents: Doesn't require metabolic conversion May be more efficient than pyridoxine May be better for some types of infantile seizures May be better for sideroblastic anemia Skeptics: Not well studied in humans Causes digestive issues in some patients May suppress prolactin and growth hormone May not be safe for pregnant women
Medication use is a common cause of hyperprolactinemia, and it is important to differentiate this cause from pathologic causes, such as prolactinomas. To ascertain the frequency of this clinical problem and to develop treatment guidelines, the medical literature was searched by using PubMed and the reference lists of other articles dealing with hyperprolactinemia due to specific types of .
A recent study [65] has proposed that vitamin B 6 could reduce prolactin levels, and therefore, the effectiveness of vitamin B 6 for reducing serum prolactin in patients with hyperprolactinemia.
Here is a more structured outline of its benefits: Vitamin B6 Deficiency. A P5P deficiency can cause problems in the nerves, skin and blood. Anemia (a lack of iron in your blood) is one possibility. ( x) Signs of pyridoxine deficiency include diarrhea, rash and even dementia. ( x ) ( x ) Nausea and vomiting may also occur, leading to poor .
Purpose: This article aims to evaluate management options for antipsychotic-induced hyperprolactinemia and associated treatment considerations such as efficacy, tolerability, drug interactions, contraindications, and dosing regimens. Summary: Hyperprolactinemia is a common adverse effect of antipsychotics. First-line management includes reducing the dose of the offending antipsychotic .
So I developed anorgasmia from low dose 150mg week nandrolone with 500 test even though my prolactin levels were well within normal range. I was taking 300mg p5p daily to try and avoid any prolactin issues which kept it in range but obviously didn't stop symptoms. I could not cum. Went 3 weeks of having sex everyday and couldn't finish one .
P5P (and dosage) in treating high prolactin Hi, my prolactin levels came up at a 40 ng/ml (Im a dude, am also not pregnant surprisingly) I spoke to my doctor about it and he completely dismissed it and told me to have an MRI and potentially get cabergoline.
Increase your zinc intake with a 25-40 milligram supplement. A zinc supplement may also help lower your prolactin levels. Try starting with 25 milligrams per day and increasing as needed to 40 milligrams per day. Have your prolactin levels rechecked to see if you need to increase the dose.
#1 So I've been doing some reading about B6 and it's lowering of prolactin at about 500-600mg but from what I've found P5P (pyridoxal 5 phosphate) at 70mg is the equivalent to 750mg B6 but there's limited information on it otherwise.
How do you dose it? I'm trying 100mg twice daily but they seem to make me feel really sick for an hr or two after taking them. Will it work if the dose is more spread out? maxmuscle1 Board Rep Joined Apr 4, 2015 Messages 25,533 Reaction score 22,607 Jul 19, 2020 #2 FLsnakeman said: does anyone use this? How do you dose it?
What I bought was 'now' brand p-5-p 50mg, however the breakdown is 33mg of B-6 (from 50mg coenzyme pyridoxal-5-phosphate monohydrate) and 25mg Magnesium (from magnesium bisglycinate). So many posts in this and other forums (supplements, peds etc) say too high of B-6 can be neurotoxic, though most feel p-5-p specifically is not.
Learn many uses and benefits of P5P, a bioavailable form of Vitamin B-6 for conditions like carpal tunnel, nerve pain, edema, anxiety, and insomnia. . Dosage. 50 mg of P5P taken 3 times a day will slowly heal a trigger finger. . "Helps lower prolactin. Helpful for the ability to reach orgasm in males and females. " Edema
Psychiatry, 26 August 2021 Sec. Psychopharmacology Volume 12 - 2021 | doi/10. 3389/fpsyt. 2021. 681418 Safety and Efficacy of High-Dose Vitamin B6 as an Adjunctive Treatment for Antipsychotic-Induced Hyperprolactinemia in Male Patients With Treatment-Resistant Schizophrenia
Safety and Efficacy of High-Dose Vitamin B6 as an Adjunctive Treatment for Antipsychotic-Induced Hyperprolactinemia in Male Patients With Treatment-Resistant Schizophrenia - PMC Journal List Front Psychiatry PMC8426548 As a library, NLM provides access to scientific literature.
P5P's effectiveness at reducing prolactin based gyno I read in a few places that p5p (vitamin b6) can help reduce prolactin, and with it gyno. I have strictly prolactin based gyno, has anyone tried this and had success? If so at what dose and how effective was it for you? This thread is archived
Lots of canning salt and calcium (dairy, eggshell) are also use to reduced prolactin. No, I won't be doing bloodtests but have been suffering from some tightness in breasts which points to prolactin for me. I use around 2 tsp salt/day. I have 25mg p5p tabs, will start with half of one. Jun 16, 2017.
[deleted] P5P for lowering prolactin? (Activated version of Vitamin b6) I have had elevated prolactin for sometime and have tried chasteberry extracy to lower it but no luck. So I've been reading people use up to 200mg of P5P to lower or regulate their prolactin levels.
Also what dosage of P5P isn't toxic? Apparently B6 is toxic when used at the dosages recommended for prolactin lowering. Is this true? And what P5P dosage would be safe for lowering prolactin? Thank you This thread is archived New comments cannot be posted and votes cannot be cast 4 4 4 comments InfiniteLlamaSoup • 1 yr. ago
First-line management includes reducing the dose of the offending antipsychotic, discontinuing the antipsychotic, or switching to another antipsychotic associated with a lower risk of hyperprolactinemia. . Upon evaluation of the available literature we found the following: (1) aripiprazole is safe and effective in lowering prolactin levels .
For best results, use 200mg P5P ED, 1200mg SAMe ED (divided doses), and 400mg Vitamin E ED. I was injecting daily with 50mg Tren A (along with 50mg Test P and 50mg Mast P), and still had some issues. After a bit more reading on here, my issues might have been E2 rather than prolactin related.
Now for the uninitiated, what P5P is for, is for anti prolactin, so pretty much anytime I'm going to be using a 19 nor, like Deca, NPP, high dosages of tren, I would need to use some kind of anti prolactin. Now for some of us, we don't have access to Cabergoline. Completely understandable for some of us, we don't really have access to that.