Astragalus Kidney Repair - Renal protective effects of astragalus root in rat models of chronic .

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Helene Nunlee

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Dec 7, 2023, 2:48:20 PM12/7/23
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Introduction. Radix astragali has been widely used as a diuretic for thousands of years and is widely distributed in temperate regions worldwide 1. Astragalus polysaccharides (APSs) are the main medicinal active ingredients in Astragalus membranaceus. APSs exert antioxidant, antitumor, anti-aging, cardiovascular protective, liver protective, and kidney protective effects 2, 3.



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Repair Effects of Astragalus Polysaccharides with Different . - Nature

Anti-inflammatory & Antioxidant Inflammation and oxidative damage are two of the key contributory factors to the development and progression of CKD regardless of the cause. Astragalus has both anti-inflammatory and antioxidant actions which plays a role in healing the kidneys and preventing further damage from occurring. Anti-fibrotic

Clinical efficacy and safety of astragalus injection. : Medicine

Macroautophagy/autophagy contributes to maladaptive kidney repair by inducing pro-fibrotic factors such as FGF2 (fibroblast growth factor 2), but the underlying mechanism remains elusive. Here, we show that EGR1 (early growth response 1) was induced in injured proximal tubules after ischemic acute k …

Effects of Astragalus membranaceus-based Chinese Medicine Formulae on .

Astragalus mongholicus Bunge and Panax notoginseng formula (A&P) improves renal mesangial cell damage in diabetic nephropathy by inhibiting the inflammatory response of infiltrated macrophages | BMC Complementary Medicine and Therapies | Full Text Research Open access Published: 20 January 2022

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Astragalus (Huáng Qí): Benefits, Side Effects and Dosage - Healthline

Astragalus membranaceus is a traditional Chinese herbal medicine with potent anti-fibrotic properties and is commonly used for strengthening the immune system, improving cardiovascular function, and enhancing vitality ( 3 ).

Astragalus root, kidney failure, chemotherapy, immune boosting

Background Astragalus root is a commonly used herb in traditional Chinese medicine. Although renoprotective effects have been reported in some clinical and experimental studies, the details remain unknown. Methods We used 5/6 nephrectomized rats as chronic kidney disease (CKD) models. At 10 weeks, they were divided into four groups, namely, CKD, low-dose astragalus (AR400), high-dose .

Dr. T Hughes III, MD, Urology | Odessa, TX | WebMD

Summary Astragalus is an herbal supplement that has been used for centuries in traditional Chinese medicine. It's purported to enhance the immune system and reduce inflammation. It's also used to.

Astragalus for Kidneys - Dr. Alexander Heyne

In this self-controlled case series, we aimed to investigate the variation in estimated glomerular filtration rate (eGFR) after taking astragalus-containing preparations in patients with mild to moderate chronic kidney disease (CKD) by retrospectively reviewing their charts in our clinic.

Efficacy, safety and response predictors of adjuvant astragalus for .

Oral Astragalus Root Supplementation for Mild to Moderate Chronic Kidney Disease: A Self-Controlled Case-Series - PMC Journal List Front Pharmacol PMC8921640 As a library, NLM provides access to scientific literature.

Astragalus (a traditional Chinese medicine) for treating chronic kidney .

Antivirals: Theoretically, astragalus may change the effectiveness of antiviral medications such as acyclovir and amantadine. ; Blood pressure medications: Astragalus can lower blood pressure. It could cause dangerously low blood pressure if combined with hypertension medications. Cancer treatments: In mice, astragalus suppresses estrogen, so it may reduce the effectiveness of certain cancer .

Astragalus and its Role in Chronic Kidney Disease

This study investigated the repair effects of three Astragalus polysaccharides (APSs) with different molecular weights (Mws) on injured human renal proximal tubular epithelial (HK-2) cells to.

Dr. Joy Okwuwa, MD - Nephrology Specialist in Odessa, TX - Healthgrades

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Dr. Anand Reddy, MD, Nephrology | Odessa, TX | WebMD

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Astragalus (a traditional Chinese medicine) for treating chronic kidney .

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Astragalus mongholicus Bunge and Panax notoginseng formula (A&P .

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Autophagy activates EGR1 via MAPK/ERK to induce FGF2 in renal . - PubMed

AM (root) and its effective components are effective in reducing fasting blood glucose and albuminuria levels, in reversing the glomerular hyperfiltration state, and in ameliorating the pathological changes of early DN in rat models. Albuminuria / drug therapy Antioxidants / pharmacology Antioxidants / therapeutic use* Astragalus propinquus*

Repair Effects of Astragalus Polysaccharides with Different Molecular .

Astragalus combats inflammation and oxidative stress, key factors in kidney disease progression. Its potent anti-inflammatory properties alleviate kidney tissue burden, while strong antioxidants protect cells and support renal health.

Oral Astragalus Root Supplementation for Mild to Moderate Chronic .

Dr. Joy Okwuwa, MD is a nephrology specialist in Odessa, TX and has over 16 years of experience in the medical field. She graduated from UNIVERSITY OF BENIN / COLLEGE OF MEDICAL SCIENCES in 2006. She is affiliated with medical facilities such as Scenic Mountain Medical Center and Medical Center Hospital. Her office is not accepting new patients.

Promoting Plant-Based Therapies for Chronic Kidney Disease

ic kidney disease (DKD) in China. However, no supporting evidence yet exists with regard to the safety and effectiveness of this approach. Here a protocol is outlined for use in systematic evaluation of the safety and effectiveness of astragalus injection combined with ACEI/ARB for the treatment of DKD. Methods: Randomised controlled trials will be retrieved from 8 scientific databases .

Astragalus Uses, Benefits & Side Effects - Drugs. com

The most common causes of CKD are aging, male gender, diabetes, hypertension and lifestyle. 10 Common pathogenetic mechanisms include tubulointerstitial fibrosis and chronic inflammation, tubular atrophy, glomerulosclerosis and proteinuria. 11 Chronic inflammation occurs through a series of biological signaling pathways involving the vasculature.

Oral Astragalus Root Supplementation for Mild to Moderate Chronic .

Astragalus, commonly known as huang-qi, is the most prescribed CM or used dietary herb in China for diabetes and DKD. In vivo and in vitro studies showed that astragalus ameliorated podocyte apoptosis, foot process effacement, mesangial expansion, glomerulosclerosis and interstitial fibrosis.

Astragalus: Benefits, Side Effects, Dosage - Verywell Health

Abstract Background Astragalus ( Radix Astragali, huang qi) is the dried root of Astragalus membranaceus (Fisch. ) Bge. var. mongholicus (Bge. ) Hsiao or Astragalus membranaceus (Fisch. ) Bge. (Family Leguminosae). It is one of the most widely used herbs in traditional Chinese medicine for treating kidney diseases.

Systematic review of the renal protective effect of Astragalus . - PubMed

Astragalus (a traditional Chinese medicine) for treating chronic kidney disease 2014 Oct 22; (10):CD008369. doi: 10. 1002/14651858. CD008369. pub2. Hong Wei Zhang 25335553 10. 1002/14651858. CD008369. pub2 This review evaluated the benefits and potential harms of Astragalus for the treatment of people with CKD.

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