Few tidbits and me fumigating my wisdom on the topic at hand ;)
* Cracks, gaps, seals, doorways, etc., are not super important; they need to be air-tight. Why? Because they will provide fresh air to the printer. The main job is to run *ALL* the air into and through the carbon chamber as many times as you can. In fact, keep it on for about oh say 5-10 mins, even 30 if you want, after the print is finished to clean up the air.
* Want to make the filtration even more effective? CLEAN THE INSIDE WALLS before long printing. Why? VOCs will STICK to clean surfaces more readily and faster than to dirty surfaces. That equates to LESS the carbon filter has to remove. I have tested this time and time again, and dirty inside means I smell it faster. Clean inside means less smelly.
* CHANGE the carbon pellets often, like every 50 hours or 30 days. I find that on my system, I would change it more often than that. Use your nose; if you smell it, then change the filter, i.e., pellets. Volume of VOCs produced is directly related to your flow rate, not temperature, but how fast it runs through the nozzle. Want to play it safe with smells? A lower flow rate will take some of it off. Also, a Rapido 2 UHF hotend pushing max flow rate on ABS really stinks. Ask me how I know ;)
* DO *NOT* use carbon pellets that contain acid. Many of them do, and you will F&^K up your printer and destroy it; that acid will eat everything and will have a ton of rust. Want to make acid even more potent? Enclose it in something and keep bouncing it around. Everything inside that will die a horrible death.
* Also, again, venting VOCs just smears it around, and yes, it can come back inside for you to breathe. It's better to trap it, neutralize it, and turn it into something you can handle more safely.
* That "new' smell you have in things? Yea that's VOC, those air fresheners for cars? yup, VOC. That new-car smell is a phthalate plasticizer, etc. It is present in most 'new' things, too. In fact, this is why a new print build plate is dirtier than a used plate ;) It's the stuff that makes plastic soft. It leeches out, and when that happens, the plastic is no longer soft and is now hard.