AddNom error with .hic file genereated by mega.sh

[Sui Pinpin]

Hello,

I combine 2 biological replicaitons by running mega.sh. But the newly generated hic file can't be normalized with AddNorm.  The first few resolutions can run, but an error is reported when the resolution reaches 100,000. I use the latest Juicer version  and JDK11 on ubuntu and centOS.

Would you like to help find the reason?

Thank you!

My commonds and errors are as below:

juicer_tools addNorm combine_WT_inter_30.hic

Calculating norms for zoom BP_2500000
Calculating norms for zoom BP_1000000
Calculating norms for zoom BP_500000
Calculating norms for zoom BP_250000
Calculating norms for zoom BP_100000

java.util.zip.DataFormatException: incorrect header check
        at java.base/java.util.zip.Inflater.inflateBytesBytes(Native Method)
        at java.base/java.util.zip.Inflater.inflate(Inflater.java:385)
        at org.broad.igv.util.CompressionUtils.decompress(CompressionUtils.java:87)
        at org.broad.igv.util.CompressionUtils.decompress(CompressionUtils.java:56)
        at juicebox.data.DatasetReaderV2.decompress(DatasetReaderV2.java:1032)
        at juicebox.data.DatasetReaderV2.readBlock(DatasetReaderV2.java:980)
        at juicebox.data.DatasetReaderV2.readNormalizedBlock(DatasetReaderV2.java:922)
        at juicebox.data.iterator.ContactRecordIterator.hasNext(ContactRecordIterator.java:85)
        at juicebox.data.iterator.CoupledIteratorAndOffset.hasNext(CoupledIteratorAndOffset.java:44)
        at juicebox.data.iterator.BigContactRecordList.populateListOfListsFromSingleIterator(BigContactRecordList.java:41)
        at juicebox.data.iterator.ListOfListGenerator.lambda$populateListOfLists$0(ListOfListGenerator.java:91)
        at juicebox.tools.dev.ParallelizedJuicerTools$1.run(ParallelizedJuicerTools.java:42)
        at java.base/java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1128)
        at java.base/java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:628)
        at java.base/java.lang.Thread.run(Thread.java:834)
java.util.zip.DataFormatException: incorrect header check
        at java.base/java.util.zip.Inflater.inflateBytesBytes(Native Method)
        at java.base/java.util.zip.Inflater.inflate(Inflater.java:385)
        at org.broad.igv.util.CompressionUtils.decompress(CompressionUtils.java:87)
        at org.broad.igv.util.CompressionUtils.decompress(CompressionUtils.java:56)
        at juicebox.data.DatasetReaderV2.decompress(DatasetReaderV2.java:1032)
        at juicebox.data.DatasetReaderV2.readBlock(DatasetReaderV2.java:980)
        at juicebox.data.DatasetReaderV2.readNormalizedBlock(DatasetReaderV2.java:922)
        at juicebox.data.iterator.ContactRecordIterator.hasNext(ContactRecordIterator.java:85)
        at juicebox.data.iterator.CoupledIteratorAndOffset.hasNext(CoupledIteratorAndOffset.java:44)
        at juicebox.data.iterator.BigContactRecordList.populateListOfListsFromSingleIterator(BigContactRecordList.java:41)
        at juicebox.data.iterator.ListOfListGenerator.lambda$populateListOfLists$0(ListOfListGenerator.java:91)
        at juicebox.tools.dev.ParallelizedJuicerTools$1.run(ParallelizedJuicerTools.java:42)
        at java.base/java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1128)
        at java.base/java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:628)
        at java.base/java.lang.Thread.run(Thread.java:834)

[Sui Pinpin]

Dose anyone know how to solve it?

Thank you!