Dear all,
as I am aiming to identify promoter-enhancer loops in a HiC dataset by using resolutions of 5kb, 10kb, 25kb, I would like to ask a basic question please :
<> given these resolutions of 5kb, 10kb, 25kb, is it fair to say that the anchors of the loops may imprecisely be localized within a mean of (5+10+25 / 3 = 13kb ) ?
<> in other words, shall we have a loop with Anchor A and Anchor B,
and an enhancer within 13kb away from Anchor A, can we assign Anchor A to that enhancer ?
or, shall we have both a promoter and enhancer with 13kb of Anchor A, can we assign both the promoter and the enhancer to the Anchor A ?
thanks a lot !