On a side note, for a long time Chrome wasn't really an option for people using Mandatory Profiles, they seem to have fixed the bug now letting you set the users data directory to store somewhere that persists, like students home drive.
My settings (for students)
Disable syncrhonization of data with Google (stops the login prompt)
Import bookmarks from default browser on first run - Disabled
Import browsing history from default browser on first run - Disabled
Import of homepage from default browser on first run - Disabled
Import saved passwords from default browser on first run - Disabled
Import search engines from default - Disabled
Incognito mode availability - Incognito mode disabled
Set Chrome as Default Browser - Enabled
Set disk cache directory - Enabled ( ${local_app_data}\Google\Chrome\User Data\Default )
Set user data directory - H:\Windows\Chrome
Show home button on toolbar - Enabled
Configure the home page URL - Enabled
Startup pages/Action on startup - Open a list of URLs
etc