On Wednesday, March 25, 2015 at 3:29:05 PM UTC-4, Bill wrote:
> A question occurs: At the beginning of an evolutionary
> sequence, the numbers of possible genetic combinations are,
> effectively, infinite.
Ridiculous. You are constrained by a multitude of factors, such as the length of your piece of genetic material, the fact that you've only got 4 nucleotides to work with, and most important, not all combinations work.
> As time passes the actual
> combinations realize some possibilities and, in so doing,
> reduce the total number of possibilities.
>
As time passes and the length of, say, a prokaryotic chromosome increases, the number of possibilities increases.
> As more combinations are realized, the number of
> possibilities shrinks in a kind of inverse proportion. What
> can possibly be a next step in an evolutionary sequence is
> dependent on the steps already realized. There can be no
> evolutionary do-overs making the whole process one way only.
The odds of going backward are quite slim, but not insurmountable. Have you ever heard of a back-mutation? When dealing with complex characters, I will grant the chances of going backwards are so infintesimal they are not worth considering.
>
> While there was a time and an environment where anything was
> possible, it is long gone and everything now is fixed in its
> probable outcomes. At some point genetic entropy takes over
> and evolution can only rearrange things and novelty becomes
> impossible. See:
>
Except for when novelty is possible. Ever hear of mutation? Gene duplication?
Chris
>
http://misplacedfacts.org/entropy.html
>
> Bill