I know that the IDiot junk DNA argument didn't make the top 6 and it is
worse than the junk that failed the scientific creationists over 30
years ago that made the top of the IDiot list of evidence for
intelligent design, but the salamander genome has been published last
month. Salamanders have very large genomes compared to other terrestial
vertebrates. The one that they sequenced has a genome 10 times the size
of the human genome, but it isn't tetraploid like it's relatives that
are over 30 times the size of the human genome.
https://www.nature.com/articles/nature25458
This genome is around 32 gigabases in size (the human genome is 3
gigabases). What they found was that the whole genome is expanded.
Genes are much bigger. The salamander genome has about as many genes as
a human. The coding sequences aren't any larger, but the introns (the
sequence between the coding bits that are cut out of the RNA and thrown
away to make the final mRNA) are 10 times as large as in humans. This
means that salamanders have to transcribe a whole lot more RNA to make
the same mRNA and express the same genes. The introns in this
salamander are over 20 thousand base pairs while humans have introns
around 2 thousand and birds average half that of humans. It turns out
that the genome is so huge because of repetitive elements. Very large
retrotransposons make up more than half the genome, my guess is that
most of the other half are ancient transposable elements that have
mutated into random sequence, and are no longer recognizable.
The IDiot argument against junk DNA is a pretty stupid argument, and
that is why it didn't make the grade above known creationist failures
like abiogenesis and fossil gap denial. The salamander genome is just
another reason why the junk DNA IDiot argument is pretty much worthless.
Here is another paper on intron size of other organisms so you can see
how much larger introns of over 20 thousand base-pairs are.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490418/
Ron Okimoto