I found a total of 39 tight superpermutations on 5 symbols, which is an exhaustive list of those meeting the following conditions:
• Only edges of weights 1 and 2
• No consecutive edges of weight 2
• The initial 10 edge weights are 1 1 1 1 2 1 1 1 1 2
• The total length of the string is 154
All 39 of these end at 53412.
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