Hi,
pyqtgraph should run with PyQt5 only. The dependency is just in the package file, not in pyqtgraph itself.
I haven't tried to use it with PyQt5 only, but if it doesn't recognize the PyQt installation, try to force the Qt library setting before importing pyqtgraph with:
import os
os.environ['PYQTGRAPH_QT_LIB'] = 'PyQt5'
Cheers
Sebastian