As described in a different thread, I have been a satisfied user of Gentoo Linux for 15+ years, and I am really charmed (deformed ? Miss-educated?) of the idea of installing software from source. Sure, it is more work than most other distributions, 2 or 3 times per year there is some major problem but overall, it's been interesting.
I guess that if one can make "linux kernel + portage = gentoo" then one could also contemplate "minix kernel + portage"; the portage system would take care of downloading and configuring, then compile the source. In this way, one could perhaps make a very modern computer environment based on Minix?