Based on this link, I would say yes. It looks like there is nothing special about Enron Modbus.
http://control.com/thread/1026233164
You would have to handle addressing yourself in your code to make sure that you don’t use an address the incorrect way for 32-bit values.
Chuck Watson BS, CEM, CMVP
Direct USA 724-799-1529
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Have you tried modbus_write_register. It uses a different function code than modbus_write_register.
http://libmodbus.org/docs/v3.0.6/modbus_write_registers.html
Chuck Watson