Hello,
the only times those EPSG codes are actually used by LAStools are:
* you are reprojecting from EPSG code one to another with las2las
* you are adding the OGC WKT string with las2las
* you want *.prj files auto-produced for your SHP vector outputs
* you want *.prj files auto-produced for your ASC/BIL/XYZ raster outputs
* you want to pass the lasvalidate check
* you want to automatically create KML files to be able to look at your outputs in Google Earth
If LAStools cannot determine what the datum is then WGS84 is used by default, so you should be fine. But maybe we should "hand-tweak" my EPSG code tables to rid you of this error. Could you send a full lasinfo report of one of your LAS / LAZ files in question?
Regards,
Martin @rapidlasso