I know there's been a lot of discussion on this and I have followed numerous threads and website postings as to how to get Circos (or more specifically, Circos' dependencies) installed on Mac OS X to no avail.
I've installed libpng and jpeg (jpeg-8d, specifically).
The problem, of course, is installing GD.
** Configuration summary for libgd 2.1.0:
Support for Zlib: yes
Support for PNG library: yes
Support for JPEG library: yes
Support for VPX library: no
Support for TIFF library: yes
Support for Freetype 2.x library: yes
Support for Fontconfig library: no
Support for Xpm library: no
Support for pthreads: yes
configure: creating ./config.status
config.status: creating Makefile
config.status: creating src/Makefile
config.status: creating tests/Makefile
config.status: creating tests/test_config.h
config.status: creating config/Makefile
config.status: creating config/gdlib-config
config.status: creating config/gdlib.pc
config.status: creating src/config.h
config.status: executing depfiles commands
config.status: executing libtool commands
Then, the result of make:
libtool: compile: gcc -DHAVE_CONFIG_H -I. -I/usr/local/include/libpng16 -I/usr/local/Cellar/freetype/2.4.10/include/freetype2 -I/usr/local/Cellar/freetype/2.4.10/include -I/usr/local/Cellar/libtiff/4.0.1/include -g -O2 -fvisibility=hidden -MT gd_jpeg.lo -MD -MP -MF .deps/gd_jpeg.Tpo -c gd_jpeg.c -fno-common -DPIC -o .libs/gd_jpeg.o
gd_jpeg.c:52:10: fatal error: 'jpeglib.h' file not found
#include "jpeglib.h"
^
1 error generated.
make[2]: *** [gd_jpeg.lo] Error 1
make[1]: *** [all] Error 2
make: *** [all-recursive] Error 1
So, the problem seems to be with jpeglib, but I can't figure out what the issue is or how to solve it.