More drug pricing lunacy
Kaleo Pharma jacks up the list price of its lifesaving medicine by 600%
DAVID LAZARUS
2/18/2017
The latest poster child for cruel and inhuman drug pricing is Kaleo
Pharma, maker of an emergency injector for a med called naloxone, which
is used as an antidote to save the lives of people who overdose on
painkillers.
As America’s opioid crisis reaches epidemic levels, Kaleo has jacked up
the list price for its Evzio auto-injector by 600%, soaring from $690
several years ago to $4,500, according to lawmakers.
Nearly three dozen senators wrote to Kaleo’s chief executive, Spencer
Williamson, last week to say they were “deeply concerned” about the
price hike and to note that it “threatens to price out families and
communities that depend on naloxone to save lives.”
But that’s not what caught my attention.
Rather, I was struck by the company’s answers to me about lawmakers’
concerns.
In response to emailed questions, Williamson said that although the list
price for Evzio is more than $4,000, that’s “not a true net price to
anyone ... due to numerous discounts and rebates that are negotiated in
the supply chain that make up our healthcare system.”
In other words, even though the price tag for his company’s easy-to-use,
lifesaving device is ridiculous and indefensible, there’s no need to
worry because backroom deals by assorted players in the healthcare food
chain make that price tag meaningless.
And that, in a nutshell, illustrates the lunacy of the U.S. healthcare
system.
“Our system of healthcare financing is the most cynical such system in
the world,” said Uwe Reinhardt, a healthcare economist at Princeton
University. “It starts with the opaque hospital bill and ends with the
opaque system of product pricing and the disgrace of surprise medical
bills. Americans can rightly be ashamed of these arrangements.”
There’s a good reason why U.S. drug prices are so much higher than what
people pay in other countries. Most other developed nations place limits
on how much drug companies can charge to prevent them from taking
advantage of the sick. A fair profit is fine. Price gouging is not.
In this country, drugmakers charge whatever they can get away with,
which perhaps would be tolerable if we had an efficient, transparent
marketplace in which patients benefit from robust competition and an
ability to shop around for the best price. But we don’t.
Often, we have a single provider of a drug or medical technology that,
thanks to its monopoly power, is in a position to profit handsomely from
people’s misfortune. Their message to this captive market is based on an
ugly economic principle: Pay up or suffer.
Or in some cases, pay up or die.
In his statement to me, Williamson said most people won’t pay anywhere
close to $4,000 for Evzio. Even with a high-deductible insurance plan,
he said, a patient won’t pay more than $360 and might end up paying
nothing thanks to the company’s “enhanced patient access program.”
But that isn’t price transparency. That’s a magician’s trick known as
misdirection. Williamson is saying, “Don’t look at the crazy list price
in this hand, look instead at the sweet discounts in this hand.”
The upshot is that his company’s prices remain indecipherable.
“It’s awfully hard to see much value in this opaque approach to real
drug pricing,” said Nicholson Price, an assistant law professor at the
University of Michigan who focuses on healthcare and regulation.
“Especially if we want to have patients be more cost-conscious to keep
costs down, opaque pricing does us no favors.”
What it does do, he added, is “create lots of opportunities for gaming
and middlemen.”
Kaleo’s gamesmanship isn’t new. As my colleague Melody Peterson noted in
a story about naloxone pricing last year: “Not long ago, a dose of the
decades-old generic drug cost little more than a dollar. Now the lowest
available price is nearly 20 times that.”
The reason Williamson can so confidently declare that the list price for
Evzio isn’t worth fretting about is because he knows it’s completely
arbitrary. Drug companies and hospitals routinely open their
negotiations with insurers with a made-up price and then settle for a
much lower amount, which is what the patient ultimately sees.
Unfortunately, that system, such as it is, no longer works. An
increasing number of Americans face the full cost of healthcare as a
result of high-deductible insurance plans.
Kaleo might pat itself on the back for its patient subsidies and
protections, but the reality is that somebody has to pay the company’s
bills, either the patient or the insurer. Sky-high list prices for
insurers raise premiums for everyone.
What’s to be done? At the moment, the only effective tool is public
shaming. Case in point: Mylan, which introduced a cheaper (but still
overpriced) version of its EpiPen after facing public scorn over a 500%
price increase for its epinephrine injector.
Otherwise, we can follow the example of our economic peers and impose
price caps for prescription drugs (it’ll never happen) or pass
legislation that introduces some sunlight to negotiations between
pharmaceutical companies and insurers (ditto).
My sense is that the only politically feasible solution is to empower
Medicare to negotiate drug prices with pharmaceutical companies — right
now that’s forbidden by law; thanks, Republicans — and for details of
that process to be available to anyone who wants to see them, as is the
case for most public spending.
The drug industry wouldn’t like that, of course. It prefers operating in
the shadows and keeping consumers in the dark.
Matt Schmitt, an assistant professor of strategy at UCLA’s Anderson
School of Management, said it’s easy for Kaleo’s Williamson to shrug off
a 600% markup as a fantasy number. But “the true price increase, while
perhaps not 600%, may still be very substantial,” Schmitt said.
That’s what Kaleo and all other drug companies want to keep hidden — the
deals cut behind closed doors. And they’ll do this by getting people to
focus on the magic wand in their hand, rather than the cards up their
sleeve.
This week, Kaleo reintroduced Auvi-Q, a competitor to the EpiPen. Auvi-Q
had been recalled from the market in 2015 after reports of device
malfunctions.
Kaleo’s list price for the injector is $4,500. Before the recall, it
sold for $500.
But don’t worry, the company says. That list price is meaningless.
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David Lazarus’ column runs Tuesdays and Fridays. He also can be seen
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david....@latimes.com.