It should be possible, but yes; there will be memory limitations. If you would like to take a look, the
Partial Least Squares sample application (
source here) demonstrates how to use one of the analysis classes (PLS) with wave signals. The other analysis classes should work in the same way, but it also depends on how the analysis is going to be done. One possible memory limitation issue that
might arise is due the use of multi-dimensional arrays instead of jagged arrays in the current PCA code. However, this is something that can be worked upon (and is currently being tracked at
Issue #94).