Hello there,
I am new to abyss 'sealer'. Trying it out on our new assembly.
Couldn't figure out the following from the sealer BMC bioinformatics paper. So posting it here.
(1) In this assembly we don't know the exact size/number of the gaps. This assembly has a representative 100 Ns for every gap.
Does it treat the number of Ns as the exact gap or I am wondering how does Sealer handle this?
(2) In-order to understand the gap distribution in Human reference, I downloaded GRCh38 (based on the sealer 'BMC bioinformatics' paper).
I find that the total gaps here is only 1242; while in the paper it is 237,408.
So can you advise me which is the reference that was used in the paper ?
Many thanks!
Kind regards,
Nisha