Ams,
I am working on methods that will allow this kind of solution to work on top of single file wikis in the future. It depends on features now only in the pre-release version.
Whatever the method used they need to be stored somewhere so what will serve the tikis, as Mario asks.
For example: It is possible to host a tiddlywiki file on SharePoint and use the checkin/out process to enforce one editor at a time. But for every user to have the ability to create and edit tiddlers, possibly at the same time (read only is fine) has some difficulties. However with the introduction of local storage in 5.1.20 we now have other possibilities. However they are conceptual and immature for a business solution without further development.
The only other viable alternative would be to have a NodeJS server and/or with Bob so that multiuser multiaccess can be managed.
Others will have a different perspective, so lets see if we get more ideas.
I am available for such work, but I believe there are some complexities you are not aware of.
Regards
Tony