where one selects the plugins from a list then executes an install.
To the best of my knowledge, it is possible, but the solution is not straightforward.
tiddlywiki.info fileOnce done, you can create new copies of TW using
tiddlywiki mynewwiki --build index
All the index.html produced using the above command will have your required plugins already available.
Step three is difficult to do, especially if you are new to TW.
But if you pull it off, then you simply have to enable and disable the plugins in tiddlywiki.info to get a TW of your choosing.