I love Louisiana for the giant redfish and typically do at least one trip a year down there. However, the past couple years, the conditions seem to be a bit perpetually off. The water is constantly high and dirty. I'm not sure if the guides aren't adjusting to the conditions (or don't want to adjust), or if it really is hurting the fishery. You definitely still have opportunity for awesome fishing, but it's just less consistent than it was 5 years ago.
Another option is the Mosquito Lagoon area in Florida, which may be a bit more friendly to both spin and fly fishing at the same time.