Not sure if you will be fishing from a boat, but if you are, water conditions near Point Lookout shouldn't be too bad. Water temperatures are pretty warm (81F) so if you are looking for rockfish, I suggest you look deeper for cooler, well oxygenated water with structure. Recent satellite pics and monitoring data don't show muddy water in the main river, however the heavy rains we have had in the last few days may muddy up the nearshore waters near the smaller creeks. Check out Eyes on the Bay's Click Before You Cast for recent Point Lookout conditions including temperature and oxygen profiles.
This is from Wednesday's MD DNR fishing report:
"Focal points are the rock piles above Point Lookout and to a lesser degree Buoys 70 and 72. In the lower Potomac, the steep channel edges parallel to St. Georges Island and Tall Timbers are providing good success. There are a lot of smaller striped bass in the mix, but larger fish are also being caught."
Good luck!
-Tom