Number of progeny required for QTL mapping?

[benc...@gmail.com]

 I am wondering if anyone knows a formula which can be used to predict the number of progeny required to find QTLs? I think it will need to take into account the genetic difference or number of SNPs between the two parents, and also the recombination frequency if known already. I am thinking of deriving this formula but maybe someone here knows?

[Julio Alfonso Chia Wong]

Hi benc6190, 

The info in the following webpage was useful for me: https://plant-breeding-genomics.extension.org/equation-to-estimate-sample-size-required-for-qtl-detection/

I hope it helps.

On Fri, Mar 12, 2021 at 2:50 PM benc...@gmail.com <benc...@gmail.com> wrote:

 I am wondering if anyone knows a formula which can be used to predict the number of progeny required to find QTLs? I think it will need to take into account the genetic difference or number of SNPs between the two parents, and also the recombination frequency if known already. I am thinking of deriving this formula but maybe someone here knows?

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Atentamente/Sincerely/Atenciosamente/真誠地/Искренне,

Julio A. Chia Wong
+51 930235755

Facultad de Agronomía
Universidad Nacional Agraria de la Selva

Av. Universitaria km 1.21 - Tingo Maria - Perú

[tom]

R/QTLdesign is also a nice tool for exploring mapping designs and power.

https://cran.r-project.org/web/packages/qtlDesign/index.html