'awokd' via qubes-users:
Common malware: no difference between new and used. There are regular
reports about malware-like software on newly bought laptops, installed
by the manufacturer. So you should always wipe the harddrive regardless
of whether the laptop is new or used.
Targeted attack by an adversary who intercepts the laptop before you buy
it: at least one security oriented manufacturer now offers a proces that
supposedly mitigates this, so this would supposedly be safer. But their
products are expensive and not avalaible everywhere.
If you need an affordable qubes-capable laptop a refurbished Dell
Latitude Lenovo thinkpad or similar 'bussiness' laptop is a good option.
Look on a secondhand site for refurbished + model number and you will
find them offered by bulk buying companies.