Anyone have suggestions as to what I might try next, if anything?
Thanks, will do (wrt cloning). Last backup was from april, so I'd like to recover if possible. r4.0; as to what went wrong, not sure exactly; qubes-dom0-update finished properly, but fairly soon afterwards, I experienced a hard reboot, likely due to unstable memory settings, which I had been tinkering with a bit.
So far all I've tried is to boot and/or repair the system, but I can't get the volume to mount, so haven't made any progress yet.
When I try to mount the data volume using a Fedora 29b live image, I get "can't read superblock on /dev/mapper/luks-5047683c-2a3f-463d-8538-53701743acca."
Thank you for the advice. I managed to recover 1 private image, the rest was salvageable, for whatever reason. (Even VMs that hadn't been started for days, so there must've been another issue than the one I mentioned; because if not, the only other conclusion I see is that btrfs is bizarrely fragile.)