OK, I have x2go working now. I had an ssh command in my .bash_profile on the target computer which was responsible. When I removed it, I got x2go working. I am now using x2go from a Qube based on fedora 26.
I still have the problem with the external audio card. I tried it on another computer and it works fine and of course it worked with Qubes OS 3.2. Does the latency problem in Qubes 4.0 still exist if I don't use USB for microphone/speakers but instead use the internal speakers/mic of the computer (or the headphones/computer mic jack)? What I am referring to is this documentation page:
https://www.qubes-os.org/doc/external-audio/. This seems to be saying that for things requiring high quality audio (even Skype) an external card is needed. I tried Skype test call using the mic/headphone jack and I assigned the mic to the Qube I was using and the test call went fine. So does the latency issue described on the page referenced above still exist? Before using the external audio card on Qubes 3.2 I did run into problems with the audio in audio/video conferences (the audio would drop sometimes) until I started using the external audio card.
Thanks.