I can report that i was able to install (and boot) the Qubes 4 final without any problems out of the box (no extra boot option) on my Lenovo Thinkpad T430, while installing Qubes 4 from an external dvd drive.
The same notebook already worked without problems with qubes 3.2 final. i did not change any bios settings meanwhile.
in bios, i enabled both vt options.
all the best
Kai