As seen in CDPE-2850, CD4PE's impact analysis puts a great deal of stress on the catalog_resources table doing selects against the file row. We have seen in customer cases that performance can be greatly improved if an index is added and autovacuum frequency is increased:
CREATEINDEX catalog_resources_file_idx on catalog_resources USING gin (file gin_trgm_ops) WHERE file ISNOTNULL;
ALTERTABLE catalog_resources SET (autovacuum_analyze_scale_factor = 0.01);
ALTERINDEX catalog_resources_file_idx SET (fastupdate=false);
I do not see much downside to these changes being the default.