Google Public DNS imposes certain rate, bandwidth, amplification, and other limits on queries from clients. If you are configuring clients (via DHCP or other means) to send queries to Google Public DNS directly at 8.8.8.8 and its other addresses (especially if you are using CG-NAT to map many clients onto a few public IP addresses), these rate limits are very likely responsible for the low rate of responses.
If you send high levels of traffic to our service either currently, or potentially in the future, please open a rate limit increase request, providing as much of the requested information as possible, and we can usually increase these limits within two business days.
Please remember that Google Public DNS is a service without an SLA, and we cannot commit to any level of service; while we strive to provide the service to as many people as want to use it, we cannot guarantee that all queries will receive a response.