Hi Sarina,
If I remember correctly, CUDA11.2 has known issues with quite some software packages, including Chrono::GPU. CUDA11.8 should work well. But if it's not creating problems for you, that's probably fine.
Typical problems with meshes that can affect DEM simulations might include inverted face normals (note the normals are determined by the right-hand rule, not the nodal normals in obj files, because that's for rendering), extremely spiky surfaces, double/invisible layers of surfaces, not being watertight, etc. You know I am a Rhino user. For me, usually using dir command in Rhino to check the face normals, then trying to use QuadRemesh to see if the mesh can be successfully reconstructed would reveal and provide fixes for most mesh problems. If you use other tools the process may be similar. However, I don't think the texture is a problem since Chrono::GPU won't read it anyway, and if it indeed affects, you should be able to see that in a rendering of the mesh. A side note: I forgot how well C::GPU loads the mesh if there are multiple meshes in a mesh file, but you can make sure there is only one mesh in the file to rule out this possibility.
Thank you,
Ruochun