Hi,
It depends on what you are printing. If you are using PLA, as most people will be, then a room with average ventilation will be sufficient. For some context that is an opinion based on producing risk assessments for my work.
Materials like ABS are more of an issue, but my advice would be to avoided these anyway unless you have a good reason. There is a tragic story of a teenager who died because of ABS fumes. Also if the room is stuffy and not ventilated then you might need to look closer, but for the average room and PLA there will not be an issue.
All the best,
Alistair