More on the disastrous "unintended outcomes" of gene-editing

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Mark Crispin Miller

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Jun 18, 2020, 12:35:51 AM6/18/20
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.... which is to say, more on the grave dangers posed by Bill/Melinda Gates' mad science.

MCM

Frequent loss-of-heterozygosity in CRISPR-Cas9-edited 
early human embryos  

Gregorio Alanis-Lobatoa, Jasmin Zohrenb, Afshan McCarthya, Norah M.E. Fogartya,c, Nada Kubikovad, 
Emily Hardmana, Maria Grecoe, Dagan Wells, James M.A. Turnerb, Kathy K. Niakana, 

https://www.biorxiv.org/content/10.1101/2020.06.05.135913v1.full.pdf



loss of heterozygosity
(… HEH-teh-roh-zy-GAH-sih-tee)
If there is one normal and one abnormal allele at a particular locus, as might be seen in an inherited autosomal dominant cancer susceptibility disorder, loss of the normal allele produces a locus with no normal function. When the loss of heterozygosity involves the normal allele, it creates a cell that is more likely to show malignant growth if the altered gene is a tumor suppressor gene. Also called LOH.
https://www.cancer.gov/publications/dictionaries/genetics-dictionary/def/loss-of-heterozygosity
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