I would say that the different anode styles are definitely an attempt to trade off effectiveness, visibility and ease of manufacture.
Some early nixies didn’t have an anode mesh. They just used the cage at the back. I guess this wasn’t too successful though given that all later nixies have the grid. Some (a lot of?) nixies have an additional anode, part way up the stack of digits, it is usually shaped like a 1. I have multiple types of top view nixie that have a rectangular anode grid that doesn’t cover the whole stack - these tend to be later versions of the same model, so it would seem that the design was continually being refined, which is not really surprising. Off the top of my head, the only one I can remember like this is the CD27. This tube also has the grid set two digits down in the stack. Finally, the planar ZM1350 uses a transparent coating of tin oxide as the anode grid. The technology evidenced in these tubes is quite advanced, but ultimately short lived.
My favorite anodes are the horizontal grids found in the ZM1177, ZM1175 etc., not to forget the unique grid of the ZM1212/ZM1210.