The trick here is to size the coupling capacitor appropriately, because it affects the on-time of the tube. SPICE simulation would be the best thing to do if you want to use this self-timed circuit. Larger cap = longer on-time, but also more energy to get rid of (heat).
My preference is to have everything directly controllable by your logic/CPU+software; in that case an opto-isolator will provide the isolation you get from the capacitor, without the annoyance of self-timed circuits that age over time.