Richard,
Same here! I started to experiment with the IV-21 tube and how to drive it recently. I have some drivers on the way. I don't have much experience with VFDs at the moment.. but I did light one up on the bench recently.
I used the datasheet recommended filament voltage/current on the IV-21 of about 2.7v at 35ma, and I lit up all the segments/girds manually without a driver IC. With everything on, I was able to perceive a difference in the brightness but I had to be looking for it, it was not obvious. Now in operation as a clock, as opposed to a static display with all segments on, I would expect it to be less noticeable.
The IV-21 is one of those 8 digit small calculator type tubes, the filament is about 40cm long or so. I believe the IV-22 single digit tube would have a shorter filament, and hence less of an effect? Maybe.
Keep us updated on your progress.
Regards,
-Moses