I've had a set of NOS 1992 IN18 tubes in a Blue Dream clock for about 10 months with the anti-poisoning cycle increased from 5 seconds, every 5 minutes to 10 seconds every 3 minutes. Since the Blue Dream has rigid "cup" style sockets, I loosened them up a bit via a tool of the same diameter as an IN18 pin I made, and I have not rotated the tubes, based on the rationale that they are late production and cycled very frequently (also shut down 7 hours a night). Nevertheless, tube #1 (which activates only the "1" at 12,11,10) developed cathode poisoning on the used digits. I also noticed during the Blue Dream test cycle, that the 5, for example (which had poisoning) would light partially at first, then fully). I removed the tube and applied 10ma at 170V and cleared all digits. To my surprise this tube (now back in the clock) is noticeably more red in color than the others. Is this a sign of outgassing? (possibly due to the rigid cup design of the Blue Dream?). Finally, many of the digits of the problem tube are also less crisp looking than the other 5 tubes.
Here is a photo, note how red the top of the 5 is, and how "fuzzy" the lower portion is of the left tube compared to the right.