Hi Chris,
I'm running MLO for Windows in Windows 10 and I don't experience any problem.
It doesn't give you a fix for your problem but proves that MLO runs under Windows 10.
A suggestion: export your data file in an xml format delete your data file, recreate a new one and reimport it.
If the problem is due to the structure of the data file, maybe it could fix your problem.
Otherwise, I think that the MLO support team is able to analyse your data file and could tell you if your data are corrupted.
Regards,
Alex