Paired Samples in MethylKit?

[Alexandra Livernois]

Hi Dr Akalin,

Is there is an option in MethylKit to indicate that samples are paired? Each independent subject in the experiment received both treatments, i.e. the experiment was conducted to compare a  treatment with a control, and both the control and the treatment were administered to each of three samples.

Subject	Treatment
1	Control
1	Treatment
2	Control
2	Treatment
3	Control
3	Treatment

Thank you,

Ali

Alexandra Livernois, Ph.D. | Postdoctoral Fellow, Food from Thought

Department of Pathobiology, University of Guelph | Ontario, Canada

519-824-4120 Ext. 54655 | live...@uoguelph.ca

[Altuna Akalin]

There is no option, you may try to include the pair information as a covariate but I'm not sure that will replace a proper paired analysis

Best,

Altuna

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