The logic would be something along these lines (note that you'd need to sort out the "button click" side)
# class Car(models.Model):
# two_wheeler = models.CharField(validators=[validate_comma_separated_integer_list])
import random
car = Car.objects.get(pk=1)
numbers = car.two_wheeler.split(',')
random_item = random.sample(numbers, 1)
# repeat for the other similar field(s)