Thanks for the answer Lemme! As I said, my problems appear exactly when I update django from 1.11 to django 2.2.x. With this change a lot of libraries need to update, and now I was trying to remove some of them and proving if they are the reason of this strange behavior. Before update django, all works perfectly.
Libraries who update with djnago 2.2.x are: channels, daphne, attrs, django-allauth, djnago-crispy-forms, djnago-extensions, django-taggit, psycopg2, djangorestframework, and subdomains (using a pull request for compatibility).
The problems happens with DEBUG=False, and using nginx and uwsgi, using the same configuration for django 1.11 and django 2.2.x
Greetings!