For some items it is an issue, and for some it is not- its depends on what the machine is doing when it is on and idle, and the expected life of the components. Some machines even need to be power cycled every now and then. I will give some examples below:
Laser cutter: ok to leave in an idle state, but you will run your fans/ventilation system more, meaning you will need to replace those filters more.
Spectrometer: some sepectrometers have consumable bulbs. Leaving these on will use up the life of the bulb.
Robots/cnc machines:
These should be powered up and warmed up/oiled regularly. Sometimes leaving them sedentary allows oil to dry up and gum things together, or components can rust.
You should also be aware of any material usage when the macjine is on- some machines will self lubricate or self test, which uses up machine life.
Generally
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