DIY microfluidics (at least the pump step)
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drllau
Mar 31, 2021, 4:55:06 AM3/31/21
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ARC-supported researchers have developed a simple pressure pump, made from balloons and nylon stockings, that will allow more people in more places to test water contaminants and blood samples. The ingenious device unveiled in the prestigious Lab on a Chip journal cost just $2 to make, yet works almost as well as its expensive and cumbersome lab counterparts.
S James Parsons Jr
Mar 31, 2021, 9:17:15 AM3/31/21
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I love this simple approach. Watch the video super cool https://www.medgadget.com/2019/07/low-cost-diy-pump-for-microfluidics-made-from-balloons-and-nylon-stockings.html
On Mar 31, 2021, at 4:55 AM, drllau <drlawr...@gmail.com> wrote:
<rh_20190730_diy_pump.jpg>
ARC-supported researchers have developed a simple pressure pump, made from balloons and nylon stockings, that will allow more people in more places to test water contaminants and blood samples. The ingenious device unveiled in the prestigious Lab on a Chip journal cost just $2 to make, yet works almost as well as its expensive and cumbersome lab counterparts.
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<rh_20190730_diy_pump.jpg>
Simon Quellen Field
Mar 31, 2021, 9:29:50 AM3/31/21
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It seems like using a basketball might be even simpler, if a bit more expensive.
And it can probably hold higher pressures.
The article was short on details like the pressure they used, how it was inflated, the nature of any valves, etc.
A basketball is normally inflated to about 8 psi (55 kilopascals) and has a volume of a little over 7 liters.
You could inflate it with the usual needle, and provide the rest of your equipment with their own needles so that it is easy to simply insert the needle when you want some pressure.
A 2-liter soda bottle can hold 150 psi (over a thousand kilopascals). Using half that number for safety still provides plenty of pressure, for even less money than the $2 balloon and nylon stockings.
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Daniel C.
Mar 31, 2021, 6:52:55 PM3/31/21
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Surely there are contamination concerns?
On Wed, Mar 31, 2021, 2:55 AM drllau <drlawr...@gmail.com> wrote:
ARC-supported researchers have developed a simple pressure pump, made from balloons and nylon stockings, that will allow more people in more places to test water contaminants and blood samples. The ingenious device unveiled in the prestigious Lab on a Chip journal cost just $2 to make, yet works almost as well as its expensive and cumbersome lab counterparts.
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drllau
Mar 31, 2021, 9:26:52 PM3/31/21
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> Surely there are contamination concerns?
which is why you pay a massive premia for lab-grade pumps with stringent quality control in ISO 14644 - FS-209E audited clean room. It all comes down to the perception of "risk" which is why PHB people never get fired (in the past) for buying IBM as you are justifying mental assurance from the "brand". This assurance may or may not be justified in reality but then we all suffer from cognitive biases (aka mental laziness). This effect is also seen in FOMO venture capitalists who jump on the latest fad without applying some critical thinking or doing the necessary legwork. But if you had to do emergency open heart self-surgery, you are more likely to have a balloon and stockings handy than a piece of lab equipment.Simon Quellen Field
Mar 31, 2021, 9:46:58 PM3/31/21
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I can think of a few ways to overcome the contamination issue.
- I'll bet you could autoclave a latex balloon and nylon stockings.
- You could have the air bubble up through a bottle of bleach with a two-hole stopper.
- You could skip the whole thing and use a bottle of hydrogen peroxide with a catalyst to create a flow of oxygen.
- You could use a bottle of lye and some aluminum foil to create a flow of hydrogen.
On Wed, Mar 31, 2021 at 6:26 PM drllau <drlawr...@gmail.com> wrote:
> Surely there are contamination concerns?
which is why you pay a massive premia for lab-grade pumps with stringent quality control in ISO 14644 - FS-209E audited clean room. It all comes down to the perception of "risk" which is why PHB people never get fired (in the past) for buying IBM as you are justifying mental assurance from the "brand". This assurance may or may not be justified in reality but then we all suffer from cognitive biases (aka mental laziness). This effect is also seen in FOMO venture capitalists who jump on the latest fad without applying some critical thinking or doing the necessary legwork. But if you had to do emergency open heart self-surgery, you are more likely to have a balloon and stockings handy than a piece of lab equipment.--On Thursday, 1 April 2021 at 06:52:55 UTC+8 Dan wrote:Surely there are contamination concerns?On Wed, Mar 31, 2021, 2:55 AM drllau <drlawr...@gmail.com> wrote:
ARC-supported researchers have developed a simple pressure pump, made from balloons and nylon stockings, that will allow more people in more places to test water contaminants and blood samples. The ingenious device unveiled in the prestigious Lab on a Chip journal cost just $2 to make, yet works almost as well as its expensive and cumbersome lab counterparts.
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Daniel C.
Apr 1, 2021, 3:33:11 PM4/1/21
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I'm more concerned about chemical than biological contaminants. Supposedly this is for testing for contaminants on a microfluidics chip. How can you know whether your contaminants are from the water source or from the pump?
On Wed, Mar 31, 2021, 7:26 PM drllau <drlawr...@gmail.com> wrote:
> Surely there are contamination concerns?
which is why you pay a massive premia for lab-grade pumps with stringent quality control in ISO 14644 - FS-209E audited clean room. It all comes down to the perception of "risk" which is why PHB people never get fired (in the past) for buying IBM as you are justifying mental assurance from the "brand". This assurance may or may not be justified in reality but then we all suffer from cognitive biases (aka mental laziness). This effect is also seen in FOMO venture capitalists who jump on the latest fad without applying some critical thinking or doing the necessary legwork. But if you had to do emergency open heart self-surgery, you are more likely to have a balloon and stockings handy than a piece of lab equipment.--On Thursday, 1 April 2021 at 06:52:55 UTC+8 Dan wrote:Surely there are contamination concerns?On Wed, Mar 31, 2021, 2:55 AM drllau <drlawr...@gmail.com> wrote:
ARC-supported researchers have developed a simple pressure pump, made from balloons and nylon stockings, that will allow more people in more places to test water contaminants and blood samples. The ingenious device unveiled in the prestigious Lab on a Chip journal cost just $2 to make, yet works almost as well as its expensive and cumbersome lab counterparts.
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Simon Quellen Field
Apr 1, 2021, 4:20:35 PM4/1/21
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You run the test without a sample in the microfluidics chip.
If you only see a signal when the sample is there, the sample is what is contaminated.
There isn't a test for "contaminants". You have to know what you are looking for.
If you are testing water for arsenic, you are unlikely to find any in a latex balloon.
But you test with a null sample to confirm, and then you test the sample.
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