Measles "immune amnesia" curing autoimmune disorders

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Nathan McCorkle

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Feb 5, 2020, 5:04:29 PM2/5/20
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It's an idea I've thought of each time this "immune amnesia" topic comes up, but I don't see any "legitimate" discussion on it.
Digging a bit into immune amnesia, it seems the existence of that idea is even argued. Though I can't tell if those claims are legitimate either, since I mostly found search hits on blogs and websites with "doctor" in the URL (which at first reaction seem 50:50 untrustable).

Jason Bobe

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Feb 5, 2020, 5:20:36 PM2/5/20
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On Wed, Feb 5, 2020 at 5:04 PM Nathan McCorkle <nmz...@gmail.com> wrote:
It's an idea I've thought of each time this "immune amnesia" topic comes up, but I don't see any "legitimate" discussion on it.
Digging a bit into immune amnesia, it seems the existence of that idea is even argued. Though I can't tell if those claims are legitimate either, since I mostly found search hits on blogs and websites with "doctor" in the URL (which at first reaction seem 50:50 untrustable).

This is a very cool paper, using PhIPseq to characterize antibody repertoire of people pre- and post-measles infxn, as well as people pre- and post-MMR vaccine:

and brief summary:
 

Dakota Hamill

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Feb 5, 2020, 5:28:28 PM2/5/20
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Anecdotal evidence which I'm not even sure is related but after I got mono-nuceleosis (Epstein-Barr Virus) and was bedridden for a month at 14-15 my parents said something changed about me forever.  Always lethargic and depressed, gained 80-100 pounds, and ended up getting GI problems and some kind of auto-immune inflammatory problem with a lot of blood in stool and many other issues.  https://www.mdmag.com/medical-news/can-epsteinbarr-virus-cause-autoimmune-illnesses

Fun times. 



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Dakota Hamill

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Feb 5, 2020, 5:31:59 PM2/5/20
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Not to hijack your thread Nathan, but since Veritas is dead or dying, is there anywhere to get your whole genome sequence for $1,000-$2,000 yet? 

Nathan McCorkle

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Feb 6, 2020, 3:19:30 PM2/6/20
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On Wed, Feb 5, 2020 at 2:30 PM Dakota Hamill <dko...@gmail.com> wrote:
>
> Not to hijack your thread Nathan, but since Veritas is dead or dying, is there anywhere to get your whole genome sequence for $1,000-$2,000 yet?

Oh? Their website still lists sequencing as a product:
https://www.veritasgenetics.com/myGenome

Dakota Hamill

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Feb 6, 2020, 4:52:15 PM2/6/20
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https://www.genomeweb.com/sequencing/veritas-genetics-halts-us-operations-lays-more-30#.XjyKM9ZKg60

I only know because they're in my area and heard 6 months ago people had ordered there kits and still not gotten results over a year later. I don't know what they're doing, maybe selling to someone that can actually process the samples in a timely manner.  It's tortuous having only 23andme data in promethease because it'd be cool to see the whole thing. 

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drewbug

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Feb 16, 2020, 4:32:23 PM2/16/20
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On Wednesday, February 5, 2020 at 11:31:59 PM UTC+1, Dakota Hamill wrote:
Not to hijack your thread Nathan, but since Veritas is dead or dying, is there anywhere to get your whole genome sequence for $1,000-$2,000 yet? 

On Wed, Feb 5, 2020 at 5:28 PM Dakota Hamill <dko...@gmail.com> wrote:
Anecdotal evidence which I'm not even sure is related but after I got mono-nuceleosis (Epstein-Barr Virus) and was bedridden for a month at 14-15 my parents said something changed about me forever.  Always lethargic and depressed, gained 80-100 pounds, and ended up getting GI problems and some kind of auto-immune inflammatory problem with a lot of blood in stool and many other issues.  https://www.mdmag.com/medical-news/can-epsteinbarr-virus-cause-autoimmune-illnesses

Fun times. 



On Wed, Feb 5, 2020 at 5:20 PM Jason Bobe <jaso...@gmail.com> wrote:
On Wed, Feb 5, 2020 at 5:04 PM Nathan McCorkle <nmz...@gmail.com> wrote:
It's an idea I've thought of each time this "immune amnesia" topic comes up, but I don't see any "legitimate" discussion on it.
Digging a bit into immune amnesia, it seems the existence of that idea is even argued. Though I can't tell if those claims are legitimate either, since I mostly found search hits on blogs and websites with "doctor" in the URL (which at first reaction seem 50:50 untrustable).

This is a very cool paper, using PhIPseq to characterize antibody repertoire of people pre- and post-measles infxn, as well as people pre- and post-MMR vaccine:

and brief summary:
 

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Dakota Hamill

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Feb 16, 2020, 4:46:57 PM2/16/20
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Thanks.  Anyone used them?  

I don't like the idea of uploading my medical records and diagnosis prior to getting the data all that much.  Let alone at all.   Will read more. 



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Nathan McCorkle

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Feb 20, 2020, 1:47:27 AM2/20/20
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Starting a new thread on this.

Just heard of this, supposedly, $300 genome for 30X coverage:

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Dakota Hamill

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Mar 20, 2020, 4:32:34 PM3/20/20
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Anyone tried it?  Someone just recommended it to me.  Another Church company.  I don't understand how is this different than Veritas 2.0? 

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Alex Brown

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Mar 20, 2020, 5:19:00 PM3/20/20
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I I have not tried this but you can find local test centers for the NIH "All of Us study" which will pay you $30 to get your whole genome sequenced and a variety of other biometrics are also recorded. They are still recruiting. Its an enormous clinical trial. I think they are trying to get 10 million US residents to sign up. Have not received my data yet, btw.

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