If you were in charge of your own genome...

[Yuriy]

This is a hypothetical question.
If you were in control of the human genome, What would you add, remove, trade-in from the human genomes thus human condition?

Would the change be to improve from an ailment or to augment an already healthy body?

Would the change be on a somal or gamete forming scale?

[Nathan McCorkle]

All of the above.

Here's a list of possible edits:
http://diyhpl.us/wiki/genetic-modifications/

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-Nathan

[Yuriy]

Oh wow, Thank you Nathan.

I never realized someone has been compiling a list. 

That's a huge wishlist.

Does anyone else have anything to add?

On Wednesday, November 20, 2019 at 2:15:13 PM UTC-5, Nathan McCorkle wrote:

All of the above.

Here's a list of possible edits:
http://diyhpl.us/wiki/genetic-modifications/

On Tue, Nov 19, 2019 at 11:05 AM Yuriy <yuriy...@gmail.com> wrote:
>
> This is a hypothetical question.
> If you were in control of the human genome, What would you add, remove, trade-in from the human genomes thus human condition?
>
> Would the change be to improve from an ailment or to augment an already healthy body?
>
> Would the change be on a somal or gamete forming scale?
>
> --

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> Learn more at www.diybio.org
> ---
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[Raza]

For myself, the only one I'm currently sure of is replacing my APOE4 allele with an APOE2 (other one is already APOE3), which offers relative benefits for heart disease and dementia risk, and late-age memory.

Haven't given thought to this question regarding humanity generally. The list linked above looks cool but the research seems incomplete on a per-gene basis (for genes that are mentioned, not all known effects are there), and many neural health associated genes are known to have trade-offs or conditional dependencies that make them less than straightforwardly beneficial. So y'know, don't rush into editing any of that into the global human genome unless you have an ERO stat. =P

[Andreas "Mega" Stuermer]

Large animals solve cancer by having extra copies of the Central housekeeping switch off the cell - p53. That sounds like a pretty modification. Look up "suoer p53 mice"

[Andreas "Mega" Stuermer]

Super p53 mice - typo