ValueError: connot convert float NaN to integer

[ly Andy]

Dear developers,

I encounter a issue when I run the program. The command:

python3 /home/yilei/biosoftware/DANPOS3/danpos.py dtriple 28825_WTmono1_S7_L999_R.final.bam:28827_R27mono1_S9_L999_R.final.bam

I found the line 289 in the wig.py is the height=int(m+0.5). The really problem of the above is the m maybe "NaN". Therefore, I changed the height=int(m+0.5) into height=int(0.5), and it can be run totally.

But I don't know if this modification would be introduce potential effect for the results. So, could you please give some suggestions?

Best,

Andy

[simon holzinger]

Hi Andy, 

I haven't encountered this problem yet and I can not reproduce it... 

m should be the mean coverage of the whole file (see a few lines up in the source 'm = self.mean()' ; self is a wig object --> the coverage). 

Just deleting the "m" probably has effects downstream which you don't want. 
My guess would be something with the input files as there is a "NaN" where a coverage should be...  

Best, 

Simon 

[ly Andy]

Dear Simon,

I figure out that the issue maybe result from  when you attempt to perform some mathematical operation that involves extremely small or extremely large numbers and Python simply outputs a NaN value as the result. Therefore, I think the "m", as the mean coverage of whole file, maybe involved the extremely value. I don't know how to fix it. Do you have some suggestions to handle it ?

Best,

Andy

[ly Andy]

Dear Simon,

Can you help me to fix this problem? I have been unable to solve this problem. 

Best,

Andy

ly Andy <andy12...@gmail.com> 于2023年5月31日周三 14:32写道：

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[ly Andy]

Dear Simon,

Can you help me to fix this problem? I have been unable to solve this problem. 

Best,

Andy