PSICQUIC webservices not working for Cytoscape?

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Nicholas Provart

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Dec 15, 2025, 2:38:36 PM (3 days ago) Dec 15
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Hi Cytoscape Team,

 

I am trying to retrieve PPIs through the PSICQUIC universal client built into Cytoscape but nothing is being returned. Is this a Cytoscape issue or is it the EBI (I suspect it’s an EBI issue but checking here just in case)?

 

Thanks,

 

Nick

Ruth Isserlin

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Dec 15, 2025, 2:59:29 PM (3 days ago) Dec 15
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Hi Nick, 
It looks like the whole psicquic registry, which is hosted by EBI, is down.  I can’t access the service through the browser either.  I emailed them but if you do as well, maybe it will come back up quicker.  
Intact’s load into Cytoscape feature does work though if you want a work around in the mean time.  
Thanks, 
Ruth 

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Ruth Isserlin

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Dec 16, 2025, 8:25:10 AM (2 days ago) Dec 16
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EBI fixed the registry.  PSICQUIC is working again. 
Thanks, 
Ruth 

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